SVN-438

Synthetic lipid analogues as anti-tumour agents

This line of research is divided into the following areas:

  • Biochemical and physicochemical studies in biological membranes. Alteration of the structural integrity of the membrane by exogenous manipulation and the repercussion on its functionality.
  • Interaction of xenobiotics with cellular membranes in human hepatoblastoma and glioblastoma cell lines.
  • Action mechanisms for anti-tumour agents (alkyl phospholipids) in HepG2 and U-87MG cells.
  • Alkyl phospholipids and structure and function of raft/non-raft membrane domains.
  • Analizyng the gene expression of proteins involved in lipid metabolism. Effect of alkyl phospholipids.

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