SVN-438
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Deuterated 5-trideuteromethyl-6-methyl-thioxo-2,3-dihydropyridin-4(1H)-one compounds and method for the preparation thereof

The invention defines deuterated compounds of formula (I), in which: R1 and R2 independently represent a hydrogen atom or a C1-C4 alkyl group substituted with an -OR4 group, R4 being a hydrogen atom or a phenyl-substituted C1-C3 alkyl group; an -NR5R6 group, R5 and R6 independently being a hydrogen atom, or a C1-C3 alkyl, tosyl or mesyl group; a -SR7 group, R7 being a hydrogen atom or a C1-C3 alkyl group; a -OCOR8 group, R8 being a C1-C3 alkyl or phenyl group; or a halogen atom; and D represents deuterium. The invention also defines a method for preparing said deuterated compounds, a pharmaceutical composition comprising said compounds and the use of said compounds in the pharmaceutical and analytical fields.

Nº Patente: 2352927

Fecha de concesión: 12.01.2012

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3915 /cms/places/merengue_content_info/68/3915/?lang=en 37.1789454143 -3.60868692348 Deuterated 5-trideuteromethyl-6-methyl-thioxo-2,3-dihydropyridin-4(1H)-one compounds and method for the preparation thereof /media/merengue/img/map/default_map_icon.png 1